Lusine gained extensive experience across various state and local government institutions. She has served in legal roles at the RA State Revenue Committee and the Ministry of Finance, including positions as legal counsel and senior specialist, focusing on tax, administrative, and civil law.

In the town of Meghri, she held key positions such as Head of the Civil Status Registration Office (CSRO) and Secretary of the Municipal Staff. As an attorney and public defender, she is dedicated to providing high-quality legal services and protecting the rights of socially vulnerable individuals.